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Hyaluronic acid filler in the nasolabial fold

The nasolabial fold is a line or wrinkle that forms between the nose and mouth. It is also known as the nasolabial fold, as it extends from the bottom of the nose to the sides of the lips. This furrow becomes more accentuated with the passage of time and can add years and sadden the facial expression.

The appearance of the nasolabial fold can be caused by several factors. Age is one of the main factors, since with aging, the skin loses firmness, collagen and elastin, which contributes to the formation of this furrow. Other factors include genetic inheritance, face and jaw shape, as well as constant gesticulation. The action of gravity may also influence their appearance.

The simplest, quickest and most economical way to eliminate it or reduce it considerably is by means of a hyaluronic acid filler.

Surco nasogeniano

How long do the results of injecting hyaluronic acid into the nasolabial fold last?

The duration of hyaluronic acid once injected into the nasolabial fold can vary depending on several factors. In general, the duration of the results can range from 8 to 12 months or even longer if the product is of high quality.

Hyaluronic acid is a resorbable material, which means that over time it is broken down and metabolized naturally in the body. The rate of resorption can be affected by the concentration and cross-linking of the hyaluronic acid used, as well as the individual’s location and metabolism.

It is important to keep in mind that the duration of results can also be affected by post-treatment care and individual lifestyle habits.

At Clínica Sanza we use the best hyaluronic acid we know, the one that lasts longer, the one that gives the best results.

Beware of saving money at a low-cost center, the result will not last.

Can I socialize or work the next day?

Yes, you do not need to rest unless you have a profession with risk of hitting the area. What we advise is to avoid going to the gym for the first two days.

You may have small bruises that go away in 24 to 48 hours and minimal swelling.

If you do not like the result, it is reversible

One of the fears of people who come to cosmetic medicine offices asking for a nasolabial fold filler is that they will not like the result. If you fear that your chin and jawline have too much volume or if you don’t like the shape, it can be left as it was. The most important thing with this treatment is that the result is natural and matches your face.

HYALURONIDASE ! this magic word is your peace of mind.

It is an enzyme that has the ability to degrade hyaluronic acid. In the field of aesthetic medicine, hyaluronidase is used to dissolve hyaluronic acid in cases where you do not like the result, due to complications or adverse reactions caused by hyaluronic acid dermal fillers.

How is hyaluronic acid injected into the nasolabial fold?

Hyaluronic acid is carefully injected into the skin layers using a fine needle or cannula. Sometimes several punctures are necessary to distribute the product well and obtain an optimal result.

Don’t just go anywhere. It is essential to keep in mind that learning how to inject hyaluronic acid safely and effectively requires proper training and in-depth knowledge of facial anatomy, injection techniques and the appropriate choice of hyaluronic acid for each patient. Performing these injections without proper training and experience can have risks, such as injury, swelling, bruising or allergic reactions in the patient.

Gráfico de relleno de surco nasogeniano


Men and women with loss of facial tissue volume who would like to improve facial morphology:

  • Filling of the temporal region.
  • Cheekbone augmentation or correction of the malar region.
  • Rhinomodelation
  • Nasolabial fold correction.
  • Lip augmentation and lip contouring.
  • Projection of the mandibular and maxillary angle.
  • Correction of marionette lines.
  • Chin augmentation.


Prior to a thorough examination and marking of the area to be treated, antisepsis of the region is performed, depending on the area to be treated, local anesthesia may be applied, then the product is infiltrated with needles or hypodermic cannulas of minimal caliber that do not leave marks. Finally, massage the area to distribute the product evenly.

It is a very simple, fast and minimally invasive procedure, so it does not cause pain or great discomfort to the patient and does not require time off work after the treatment.


  • Between 15-45 minutes depending on the amount placed and areas worked.



  • Evaluation of the area to determine treatment.
  • No blood tests or other tests are necessary.
  • Control photograph of the area to be treated.


  • Anesthetic cream can be applied or local anesthesia can be infiltrated to reduce discomfort; this procedure is very well tolerated by the patient.


  • Without hospitalization.


  • Do not perform intense physical activity 24hr after treatment.
  • Keep the treated area clean.
  • Do not massage the worked area.
  • No bandage required.
  • No medication is required.


  • Immediate return to work, minimal swelling or small bruises may appear in the worked area which will disappear in 24-48 hours at the most.


  • Recovery of lost tissue volume , noticeable reduction of skin flaccidity and reduction of expression lines, collagen stimulation that improves skin quality in the applied area.
  • Volume enhancement in the treated area to highlight facial features.


  • Very simple intervention.


  • Under

Before/after photos of nasolabial fold removal using hyaluronic acid

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Clínica Sanza at the forefront of aesthetic medicine treatments, is in the new era of Dynamic Aesthetics through its team of specialists.

Do not make a mistake with Botulinum Toxin!

Differences between hyaluronic acid and Botulinum Toxin video

People often confuse the two terms. This video explains very briefly the difference between botulinum toxin and hyaluronic acid. Both are used to remove wrinkles but they are not the same, one or the other should be used depending on the wrinkle to be treated and the area of the face.

Whatever your case may be, do not hesitate to contact us.
Sanza Clinic in Barcelona, quality of service


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